butabarbital will reduce the level or impact of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Influence of coadministering a powerful CYP3A4 inducer with fedratinib has not been researched.butabarbital will lower the level or result of carvedilol by influencing hepatic enzyme CYP2C9/ten … Read More